Sugar acids and derivatives
Alkali Scientific 4 Methylumbelliferyl β D cellobiopyranoside, 100 Mg
Methylumbelliferyl Cellobiopyranoside is a high-purity reagent used in biochemical analysis to assess the activity of cellulase enzymes, particularly those involved in the breakdown of cellulose and related polysaccharides. This 100mg reagent is essential for enzyme assays designed to measure the hydrolysis of cellobiose or other cellulose derivatives. It is widely utilized in studies of plant biomass degradation, biofuel production, and the enzymatic processing of agricultural and industrial waste. The high purity of this reagent ensures consistent and reliable results in laboratory experiments focusing on cellulase activity and cellulolytic enzymes.
Medchemexpress LLC D-3263 hydrochloride | 1008763-54-9 | MFCD22665741 | 98.0% | 409.95 | C21H32ClN3O3 | 10 MG
D-3263 hydrochloride is an enteric-coated, orally bioavailable agonist of transient receptor potential melastatin member 8 (TRPM8). It binds and activates TRPM8, modulates calcium and sodium flux, and has been investigated for potential antineoplastic effects and modulation of androgen-related pathways.
- Orally bioavailable TRPM8 agonist suitable for in vivo studies.
- Enteric-coated formulation for improved gastrointestinal stability.
- High purity (98.0%) supports reproducible experimental results.
- Soluble in DMSO and formulatable for common in vivo vehicles.
- Stable when stored sealed at 4°C; solvent stability at -80°C for extended storage.
Medchemexpress LLC MAC-545496 | 838810-96-1 | 98.0% | 10 MM * 1 ML
MAC-545496 is a potent nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR), demonstrating strong binding affinity (Kd ≤ 0.1 nM). It acts as an antivirulence agent, effectively reversing β-lactam resistance in Methicillin-resistant Staphylococcus aureus (MRSA) strains, and is intended for research use only.
- Potently synergizes with Cefuroxime and Oxacillin against S. aureus clinical isolates.
- Inhibits mprF expression in a concentration-dependent manner (IC50 of 0.0376 μg/mL).
- Inhibits citrate-induced biofilm formation in wild-type strains.
- Effective as monotherapy for MRSA-infected Galleria mellonella larvae, increasing survival.
Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 25 MG
BET bromodomain inhibitor 1 is an orally active and selective inhibitor of bromodomain and extra-terminal (BET) bromodomains. It demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest, inhibiting c-Myc expression, and upregulating p21 levels. Its primary applications involve research into acute myeloid leukemia, acute leukemia, and multiple myeloma.
- Orally active and selective BET bromodomain inhibitor.
- High affinity for BRD4 (IC50: 2.6 nM) and other BET bromodomains.
- Demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest.
- Effective against various cancer cell lines (Kasumi 1, MM1.S, MV4-11, and RS4-11).
- Excellent selectivity for BET bromodomain family over other bromodomains.
- Does not inhibit five cytochrome P450 enzymes.
- Exhibits strong antitumor activities in in-vivo models.
Medchemexpress LLC Saikosaponin D | 20874-52-6 | MFCD09028095 | >=90.0% | 780.98 g/mol | C42H68O13 | 10 MG
Saikosaponin D is a triterpene saponin isolated from Bupleurum used in research for its anti-inflammatory, antibacterial, antitumor, and anti-allergic activities. It has been reported to inhibit selectin-mediated binding and downstream signaling pathways including STAT3 and NF-κB, and to activate estrogen receptor-β.
- Triterpene saponin with multiple reported bioactivities including anti-inflammatory and antitumor effects.
- Suitable for in vitro and preclinical research at small mg scale.
- Molecular formula C42H68O13; molecular weight 780.98 g/mol.
- CAS number 20874-52-6 for unambiguous identification.
- Purity reported ≥90% by HPLC in vendor reference.