Sugar acids and derivatives
Apexbio Technology LLC Cytochalasin D 22144-77-0 10mg
Cytochalasin D is a selective inhibitor of actin polymerization with a reported IC50 value of approximately 25 nM It exerts its biological effect by disrupting the formation and stability of actin filaments thereby influencing cellular processes dependent on cytoskeletal organization Through this mechanistic action Cytochalasin D induces cell cycle arrest at the G1-S transition via activation of p53-related signaling pathways In neuronal studies treatment with Cytochalasin D interferes with filopodial and lamellipodial dynamics by limiting protrusion elongation Additionally in vitro investigations demonstrated its utility in the study of virus-host interactions where blockade of actin polymerization inhibits pathogen entry and replication making Cytochalasin D a relevant reagent in cellular biology and virology research
Medchemexpress LLC D-NMAPPD ((1R,2R)-B13) | 35922-06-6 | MFCD08062172 | 99.7% | 422.56 | C23H38N2O5 | 10MG
D-NMAPPD ((1R,2R)-B13) is a research-grade small molecule inhibitor of acid ceramidase. It modulates NMDA receptor properties by enhancing endogenous ceramide production and has demonstrated anticancer activity in cellular studies. For research use only; not for human or veterinary use.
- Acid ceramidase inhibitor that induces apoptosis in cell models.
- Modulates NMDA receptor function via increased ceramide production.
- CAS number: 35922-06-6.
- Molecular formula: C23H38N2O5; molecular weight: 422.56.
- High purity suitable for research: 99.7%.
- Available in solid and solution formats, including 10 MG and 10 mM in DMSO solutions.
![Medchemexpress LLC Sar-[D-Phe8]-des-Arg9-Bradykinin | 126959-88-4 | MFCD05662308 | 100.0% | 975.10 g·mol⁻¹ | C47H66N12O11 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244666.png-250.jpg)
Medchemexpress LLC Sar-[D-Phe8]-des-Arg9-Bradykinin | 126959-88-4 | MFCD05662308 | 100.0% | 975.10 g·mol⁻¹ | C47H66N12O11 | 10 MG
Sar-[D-Phe8]-des-Arg9-Bradykinin is a synthetic peptide agonist of the bradykinin B1 receptor used in pharmacology research to study B1-mediated vascular contractility and inflammatory signaling. It is supplied as a white to off-white solid with defined sequence and characterized physicochemical properties for in vitro applications.
- High purity (99.96%).
- White to off-white solid appearance.
- Molecular weight 975.10 g·mol⁻¹.
- Sequence: {Sar}-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe.
- CAS number 126959-88-4.
- Soluble in DMSO at 100 mg/mL; may require ultrasonic.
- Store sealed at -80°C (up to 2 years) or -20°C (up to 1 year).
- Available in multiple mg sizes (5 mg-100 mg).
![Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237008.png-250.jpg)
Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG
BET-BAY 002 is a research-grade small-molecule BET bromodomain inhibitor used in epigenetic and oncology research. It is supplied as a white to off-white solid (CAS 1588521-78-1) with a molecular weight of 403.86 g/mol and reported high purity for reliable experimental use. The compound dissolves readily in DMSO and has recommended storage conditions for long-term stability.
Medchemexpress LLC 4-methylumbelliferyl β-D-glucopyranoside | 18997-57-4 | MFCD00063694 | >98.0% | 338.31 g/mol | C16H18O8 | 500MG
4-Methylumbelliferyl β-D-glucopyranoside is a fluorogenic β-D-glucoside substrate for measuring β-glucosidase activity. Upon enzymatic cleavage it releases 4-methylumbelliferone (4-MU), a highly fluorescent product useful for quantitative enzymatic assays and high-throughput screening. The excitation maxima of 4-MU are pH-dependent, and the compound is provided as a white to off-white powder suitable for laboratory use.
- Fluorogenic substrate for β-glucosidase assays.
- Releases 4-methylumbelliferone with emission ~445-454 nm.
- Excitation maxima depend on pH (≈330, 370, 385 nm).
- High purity (≥98.0% by HPLC) for reliable results.
- Available in multiple pack sizes, including 500 MG.
- Molecular formula C16H18O8; molecular weight 338.31 g/mol.
Medchemexpress LLC Integrin alpha V beta 3 protein, mouse (biotinylated, HEK293, his-avi) | >=95.0% | 20UG
Integrin alpha V beta 3 protein is a recombinant, biotinylated heterodimer derived from mouse and expressed in HEK293 cells. It carries C-His and C-Avi tags and is glycosylated, producing an apparent molecular weight of approximately 90-130 kDa. The protein is provided for in vitro studies of integrin-mediated ligand binding, cell adhesion, signaling, and biochemical assays.
- Recombinant mouse integrin heterodimer, biotinylated and tag-labeled.
- Expressed in HEK293 cells to preserve mammalian glycosylation.
- Suitable for ligand binding assays, ELISA, SPR, and pull-down experiments.
- Useful for cell adhesion and endothelial migration studies.
- Purity ≥95% as determined by reducing SDS-PAGE.
- Provided in assay-ready small-volume format.
Medchemexpress LLC Heparin calcium | 37270-89-6 | MFCD00131296 | ≥98.0% | 3600-5000 | Not specified (heterogeneous polysaccharide; no single chemical formula) | 25 MG
Heparin calcium (MW 3600-5000) is a low-molecular-weight heparin anticoagulant supplied for research use. It binds antithrombin III to inactivate thrombin and other activated clotting factors, preventing fibrin formation. The material is provided as a white to off-white solid with good aqueous solubility and is intended for laboratory assays involving anticoagulation or coagulation pathway studies.
- Intended for research use only.
- Anticoagulant that binds antithrombin III to inhibit coagulation.
- Molecular weight range 3600-5000.
- Supplied as a white to off-white solid.
- Soluble in water (≈200 mg/mL with ultrasonication).
- Store sealed and dry at 4 °C; in solution, store at -20 °C to -80 °C per guidelines.
- Typical purity ≥98% (batch-specific certificate of analysis available).
- Available in small laboratory package sizes (example: 25 mg).
Cayman Chemical D-GlucuronIc AcId 100g
A metabolite of glucose; a component of proteoglycans; levels are increased in fibroblasts isolated from patients with ISSD or Salla disease